What do you do when your own worst enemy is...you? This hour, Radiolab looks for ways to gain the upper hand over those forces inside us--from unhealthy urges, to creative insights--that seem to have a mind of their own.

We meet a Cold War negotiator who, in order to quit smoking, backs himself into a tactical corner, and we visit a clinic in Russia where patients turn to a radical treatment to help fight their demons. Plus, Elizabeth Gilbert lays out strategies for doing battle with your muse.